Kaihanga paura YDL223C (HBT1) Nama CAS: 489408-02-8 99% te parakore iti rawa mō ngā kai tāpiringa

Ka herea a HBT1 ki te rohe here-ligan o te kaiwhakawhiwhi waikawa α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic (AMPA-R) i runga i te tikanga e whakawhirinaki ana ki te glutamate. Ko te tikanga o tēnei ko te HBT1 he ngota ka taea anake te here ki tētahi wāhi motuhake i runga i te pūmua AMPA-R ina kitea te glutamate, ā, ka āwhina tēnei here ki te whakahaere i te mahi a te pūmua. Ka whakaatuhia ngā kaiwhakawhiwhi AMPA puta noa i te pūnaha io matua, ā, he mahi nui tā rātou ki te whakawhitiwhiti kōrero neuronal, te tukatuka i ngā pūoko, te ako, te mahara, me te kirihou synaptic. He nui ngā kaiwhakawhiwhi AMPA ki te tuku neuroexcitatory, ka whakahaere i te whakaoho tere, te whakaiti tere i te aro i te maha o ngā synapses, ā, ka uru ki ngā urupare wawe ki te glutamate i roto i ngā rohe synaptic. He maha ngā wā ka whakaatuhia ngā kaiwhakawhiwhi AMPA me ngā kaiwhakawhiwhi NMDA i ngā synapses, ā, ka whakatairanga ngātahi rātou i ngā tukanga kirihou synaptic e uru ana ki te ako, te mahara, te excitotoxicity, me te tiaki io. Ko te take neurotrophic i ahu mai i te roro (BDNF) he take neurotrophic e whai wāhi nui ana ki te tiaki me te whakawhānui i ngā neurons, ā, he kaha, he maha hoki ōna pānga ki te tipu, te rerekētanga, te oranga me te matenga o ngā pūtau neuronal me ngā pūtau kore-neuronal. , he kaiwhakatikatika neurotransmitter e whai wāhi ana ki te kirihou o ngā neuron i roto i te ako me te mahara. Nō reira, he mea nui mō te hauora me te oranga o te pūnaha io.