I te whanaketanga o te hapori, kei te aro nui haere te tangata ki ngā take hauora. I tēnei rā ka hiahia ahau ki te whakamōhio atu ki a koutou ētahi kōrero mō te mate a Alzheimer, he mate roro e ahu whakamua ana e ngaro ai te mahara me ētahi atu pūkenga hinengaro.
Meka
Ko te mate a Alzheimer, te momo mate wareware tino kitea, he kupu whānui mō te mahara me te ngaronga hinengaro.
He mate whakamate te mate a Alzheimer, ā, kāore he rongoā. He mate mau tonu e tīmata ana i te ngaronga o te mahara, ā, i te mutunga ka arahi ki te kino nui o te roro.
I tapaina te mate nei i muri i a Tākuta Alois Alzheimer. I te tau 1906, i whakahaerehia e te tākuta mate roro he tātaritanga i te roro o tētahi wahine i mate i muri i te whanaketanga o te ngoikore o te kōrero, te whanonga kore e taea te matapae me te ngaro o te mahara. I kitea e Tākuta Alzheimer ngā papa amyloid me ngā neurofibrillary tangles, e kiia ana ko ngā tohu o te mate.
Ngā āhuatanga awe:
Tau – I muri i te 65 tau, ka piki rua te tūponotanga o te pāngia e te mate a Alzheimer i ia rima tau. Mō te nuinga o te tangata, ka puta tuatahi ngā tohu i muri i te 60 tau.
Hītori Whānau – He pānga nui tō ngā āhuatanga ira ki te mōrearea o te tangata.
Te Whara o te Upoko – Tērā pea he hononga i waenga i tēnei mate me te whara auau, te ngaronga rānei o te māramatanga.
Hauora o te ngākau – Ka taea e ngā mate ngākau pērā i te toto toto tiketike, te cholesterol tiketike me te mate huka te whakanui ake i te mōrearea o te mate wareware vascular.
He aha ngā tohu whakatūpato e rima o te mate a Alzheimer?
Ngā tohu pea: te ngaronga o te mahara, te whakahokinga o ngā pātai me ngā kōrero, te ngoikore o te whakaaro, te whakatakotoranga hē o ngā taonga, te huringa o te wairua me te tuakiri, te pōhēhē, te whakaaro pohehe me te paranoia, te whanoke, te haurangi, te uaua ki te horomi
He aha te rerekētanga i waenga i te mate wareware me te mate a Alzheimer?
He mate e pā ana te mate wareware me te mate a Alzheimer ki te hekenga o te mohio, engari he rerekētanga kei waenganui i a rāua.
Ko te mate wareware he mate e pā ana ki te hekenga o te mahi hinengaro i puta mai i ngā take maha, tae atu ki ngā tohu pēnei i te ngaronga o te mahara, te ngoikore o te kaha whakaaro, me te ngoikore o te whakatau. Ko te mate a Alzheimer te momo mate wareware tino noa, ā, ko te nuinga o ngā take mate wareware te take.
He mate neurodegenerative haere tonu te mate a Alzheimer e pā ana ki ngā kaumātua, ā, ko tōna āhua he whakatakotoranga pūmua rerekē ki roto i te roro, ka arahi ki te kino o ngā neuron me te mate. He kupu whānui te Dementia e uru ana ki te hekenga o te hinengaro i puta mai i ngā momo take, ehara i te mate a Alzheimer anake.
Ngā whakatau tata ā-motu
E ai ki ngā whakatau tata a te Centers for Disease Control and Prevention, tata ki te 6.5 miriona o ngā Amerikana e pāngia ana e te mate a Alzheimer. Ko te mate te tuarima o ngā tino take o te mate i roto i ngā pakeke neke atu i te 65 tau te pakeke i te United States.
Ko te utu mō te tiaki i te hunga e pāngia ana e te mate a Alzheimer, e ētahi atu mate wareware rānei i te Hononga o Amerika e $345 piriona i te tau 2023.
te tīmatanga wawe o te mate a Alzheimer
Ko te mate a Alzheimer e tīmata wawe ana he momo onge o te mate wareware e pāngia ana e te hunga kei raro iho i te 65 tau te pakeke.
He maha ngā wā ka pā mai te mate a Alzheimer i roto i ngā whānau wawe.
Rangahau
9 Maehe, 2014—I roto i tētahi rangahau hou o tōna momo, e ai ki ngā kairangahau kua whakawhanakehia e rātou he whakamātautau toto ka taea te matapae me te tino tika mēnā ka pāngia te hunga hauora e te mate a Alzheimer.
23 o Noema, 2016 – I panuitia e te kaihanga rongoā o Amerika a Eli Lilly ka mutu te whakamātautau haumanu Wāhanga 3 o tana rongoā Alzheimer's solanezumab. "Kāore i tino puhoi te tere o te hekenga hinengaro i roto i ngā tūroro i rongoatia ki te solanezumab ki te whakataurite ki ngā tūroro i rongoatia ki te placebo," te kī a te kamupene i roto i tētahi kōrero.
Hui-tanguru 2017 – I whakamutua e te kamupene rongoā Merck ngā whakamātautau wāhanga whakamutunga o tana rongoā mō te mate Alzheimer, arā, ko te verubecestat, whai muri i te kitenga o tētahi rangahau motuhake he "koretake te whai huatanga" o te rongoā.
28 o Pēpuere, 2019 – I whakaputa te hautaka Nature Genetics i tētahi rangahau e whakaatu ana i ngā momo ira hou e whā e whakanui ana i te mōrearea o te mate a Alzheimer. Te āhua nei ka mahi tahi ēnei ira ki te whakahaere i ngā mahi a te tinana e awe ana i te whanaketanga o te mate.
4 Paenga-whāwhā, 2022 – Kua kitea e tētahi rangahau i whakaputaina i tēnei tuhinga ētahi atu ira e 42 e hono ana ki te whanaketanga o te mate a Alzheimer.
7 Paenga-whāwhā, 2022 — I panuitia e te Centers for Medicare and Medicaid Services ka whakawhāitihia te kapinga o te rongoā Alzheimer's tautohenga, utu nui hoki, Aduhelm ki te hunga e whai wāhi ana ki ngā whakamātautau haumanu e tika ana.
4 Mei, 2022 – I whakapuakina e te FDA te whakaaetanga o tētahi whakamātautau tātaritanga mate a Alzheimer hou. Koinei te whakamātautau tātaritanga in vitro tuatahi ka taea te whakakapi i ngā taputapu pēnei i ngā matawai PET e whakamahia ana i nāianei hei tātaritanga mate a Alzheimer.
30 o Hune, 2022 – Kua kitea e ngā kaipūtaiao tētahi ira e whakaatu ana i te nui ake o te tūponotanga o te wahine ki te pangia e te mate a Alzheimer, e whakarato ana i ngā tohu hou mō te take he nui ake te tūponotanga o te tākutatanga o ngā wāhine ki te pangia e te mate i ngā tāne. He mahi nui tā te ira, O6-methylguanine-DNA-methyltransferase (MGMT), ki te kaha o te tinana ki te whakatika i ngā kino o te DNA i roto i ngā tāne me ngā wāhine. Engari kāore i kitea e ngā kairangahau he hononga i waenga i te MGMT me te mate a Alzheimer i roto i ngā tāne.
Hanuere 22, 2024—E whakaatu ana tētahi rangahau hou i roto i te puka JAMA Neurology ka taea te tirotiro i te mate a Alzheimer me te "tino tika" mā te kimi i tētahi pūmua e kiia nei ko te phosphorylated tau, ko te p-tau rānei, i roto i te toto tangata. Ka taea te mahi i te mate puku ahakoa i mua i te tīmatanga o te puta mai o ngā tohu.
Wā tuku: Hōngongoi-09-2024
