Ko te NAD+ (Beta-Nicotinamide Adenine Dinucleotide) he coenzyme e kitea ana i roto i ngā pūtau ora katoa, ā, he mea nui mō ngā momo tukanga koiora, tae atu ki te whakaputa pūngao me te whakatika DNA. I a tātou e pakeke haere ana, ka heke iho ō tātou taumata NAD+, ka hua ake he maha ngā raruraru hauora. Hei whawhai i tēnei raruraru, he tokomaha te hunga e tahuri ana ki ngā tāpiringa NAD+ i roto i te ahua paura. Heoi, he maha ngā kōwhiringa kei reira, he uaua pea te whakatau ko tēhea paura NAD+ te mea pai mōu. Ko te whiriwhiri i te paura NAD+ pai rawa atu me whai whakaaro nui ki te parakore, te wātea o te koiora, te horopeta, te māramatanga, me ngā urupare a te kiritaki. Mā te whakatau i ēnei āhuatanga, ka taea e koe te whakatau whai whakaaro me te whiriwhiri i te paura NAD+ kounga teitei e tautoko ana i tō hauora me tō oranga.
Ka puta noa te NAD i roto i ō tātou pūtau,i roto i ō rātou cytoplasm me ngā mitochondria te nuinga, heoi, ka heke ngā taumata tūturu o te NAD i a tātou e pakeke haere ana (ia 20 tau, inaa), ka puta ngā pānga noa o te koroheketanga, pērā i te hekenga o ngā taumata pūngao me te pikinga o te mamae me te mamae. Heoi anō, ko ngā hekenga e pā ana ki te koroheketanga o te NAD e pā ana ki ētahi atu mate e pā ana ki te koroheketanga, pērā i te mate pukupuku, te hekenga o te hinengaro, me te ngoikore.
Ehara a NAD+ i te homoni, he coenzyme. Ka taea e te NAD+ te whakapai ake i te kaha o te DNA ki te whakatika i a ia anō, te whakaroa i te roanga o te ora mā te whakakore i te hekenga o ngā mitochondria, me te tiaki i te kino o te DNA me te mitochondria. Ā, ka taea hoki te whakapai ake i te pumau o ngā chromosome. E mōhiotia ana hoki a NAD+ ko te "ngota merekara" e whakaora ana, e pupuri ana hoki i te hauora o ngā pūtau. I roto i ngā rangahau kararehe, kua whakaūtia he kaha tōna kaha ki te rongoā i ngā momo mate pēnei i te mate manawa, te mate huka, te mate a Alzheimer, me te momona.
Ka whai wāhi atu a NAD+ ki ngā momo tauhohenga matū koiora i roto i ngā pūtau, pērā i te glycolysis, te oxidation waikawa ngako, te huringa waikawa tricarboxylic, te mekameka manawa, me ētahi atu. I roto i ēnei tukanga, ka mahi a NAD+ hei kaikawe hauwai, e tango ana i ngā irahiko me te hauwai mai i ngā matū, kātahi ka whakawhiti atu ki ētahi atu ngota, pērā i te NADH me te FAD, hei pupuri i te taurite redox ā-roto. He mahi nui tā NAD+ i roto i te whakaputanga pūngao pūtau, te tiaki i ngā rauropi kore utu, te whakatika DNA, me te tohu.
Hei tāpiritanga, he hononga tata anō hoki tō te NAD+ ki te koroheketanga, ā, ka heke iho ōna taumata i te pakeketanga. Nō reira, he mea nui te pupuri i ngā taumata NAD+ ki te whakaroa i te koroheketanga, te whakarei ake i te pūngao, te whakatairanga i te whakatikatika pūtau, te whakapai ake i te mahi hinengaro, me te whakahaere i te pākia o te tinana.
He mea nui kia mōhiotia, ko te koroheketanga e haere tahi ana me te hekenga haere o ngā taumata NAD+ kiko me te pūtau i roto i ngā momo rauropi tauira, tae atu ki ngā kiore me te tangata.
Nō reira, mā te whakakī anō i te nui o te NAD+ i roto i te tinana i te wā tika ka taea te whakaroa i te koroheketanga, ā, ka pai ake te hauora. Ki te hiahia koe kia noho noa te pakeketanga hei tau, tāpirihia te NAD+ i te wā e taea ai kia ātaahua ai koe mai roto ki waho.
Ka heke ngā taumata NAD+ i te pakeketanga, nā te mea kāore e taea e tōna tere whakaputa te eke ki tōna tere kai.
He maha ngā rangahau kua whakaatu ko te hekenga o ngā taumata NAD+ he hononga take ki ngā mate maha e pā ana ki te koroheketanga, tae atu ki te hekenga o te hinengaro, te mumura, te mate pukupuku, ngā mate pāwera, te sarcopenia, ngā mate neurodegenerative, me ētahi atu.
Koia te take e hiahiatia ai e tātou ngā tāpiringa NAD+. Pērā i tō tātou momo collagen 3, kei te ngaro tonu.
Ka taea e te NAD+ te ātete i te koroheketanga. He aha te mātāpono kei muri?
Ka whakahohehia e te nad+ te whākōkī whakatikatika ira parp1
Āwhina i te whakatika i te DNA Ko tētahi o ngā take o te koroheketanga ko te kino o te DNA. Ko tō makawe mā, te hekenga o te ovary me ētahi atu okana, e pā katoa ana ki te kino o te DNA. Mā te noho pōuri me te ahotea ka kino ake te kino o te DNA.
Kua kitea e ngā rangahau ka āwhina a NAD+ i te whakahohe i te ira PARP1 (e mahi ana hei kaiwhakautu tuatahi ki te kite i ngā kino o te DNA, kātahi ka whakatairanga i te kōwhiringa o ngā ara whakatika. Ka ārahi a PARP1 ki te wetewete i te hanganga chromatin mā te ADP ribosylation o ngā histones, ā, ka uru atu ki ngā momo āhuatanga whakatika DNA e taunekeneke ana, e whakarerekē ana hoki i a rātou, ā, ka whakapai ake i te pai o te whakatika), ā, ka whakatika i ngā kino o te DNA me te whakatairanga i te whakaoho i ngā nekehanga pākia.
Hei whakarāpopototanga, ka taea e te NAD+ te pā tika me te kore tika ki ngā mahi matua o te pūtau, tae atu ki ngā ara pākia o te tinana, te whakatikatika i te DNA, te whakahou i te chromatin, te koroheketanga o te pūtau, te mahi a ngā pūtau ārai mate, me ētahi atu, ā, ka whakaroa i te tukanga koroheketanga o te tangata.
NAD+ Ko te kupu "Nicotinamide adenine dinucleotide" te whakarāpopototanga reo Pākehā. Ko tōna ingoa katoa i te reo Hainamana ko te nicotinamide adenine dinucleotide, ko te "Coenzyme I" rānei. Hei "coenzyme" e tuku ana i ngā katote hauwai, he mahi nui tā NAD+ i roto i ngā āhuatanga maha o te pākia o te tangata, tae atu ki te glycolysis, te Gluconeogenesis, te huringa waikawa tricarboxylic, me ētahi atu. Kua tohua e ētahi rangahau ko te whakahekenga o te NAD+ e pā ana ki te pakeketanga, ā, ko ngā tikanga ā-tinana e whakahaerehia ana e te NAD+ e pā ana ki te koroheketanga, ngā mate pākia, te neuropathy me te mate pukupuku, tae atu ki te whakahaere i te homeostasis pūtau, ngā sirtuins e mōhiotia ana ko "ngā ira roa", te whakatika i te DNA, ngā pūmua whānau PARP e pā ana ki te necroptosis me te CD38 e āwhina ana i te tohu konupūmā.
Ārai-pakeketanga
Ko te koroheketanga e pā ana ki te tukanga e mutu ai te wehewehe o ngā pūtau. Ka taea e te kino o te DNA, te ahotea pūtau rānei te whakararu i te koroheketanga. Ko te koroheketanga te tikanga whānuitia ko te tukanga o te hekenga āta haere o ngā mahi ā-tinana i te kaumātuatanga; ko ngā whakaaturanga o waho ko ngā huringa ā-tinana i puta mai i te ngaronga o ngā uaua me ngā wheua, ā, ko ngā whakaaturanga o roto ko te whakahekenga o te pākia o te tinana me te mahi ārai mate.
Kua rangahauhia e ngā kaipūtaiao ngā tāngata roa te ora, ā, e whakaatu ana ngā hua rangahau he ira e pā ana ki te roa o te ora o te hunga roa te ora - ko te "ira Sirtuins". Ka whai wāhi tēnei ira ki te tukanga whakatikatika i te pūngao o te tinana me te whakaputanga DNA hei pupuri i te pono me te pumau o te ira, te tango i ngā pūtau kua koroheke, te whakapai ake i te pūnaha ārai mate mā roto i ngā pānga ārai-mumura me te ārai-waipiro, me te whakaroa i te koroheketanga o ngā pūtau noa.
Ko te whakahohenga arotahi anake o ngā ira roa o te ora "Sirtuins" -NAD+
He mea nui te NAD+ mō te pupuri i te hauora me te taurite o te tinana. Ko te pākia o te tinana, te redox, te tiaki me te whakatikatika i te DNA, te pumau o te ira, te whakahaere epigenetic, me ētahi atu mea katoa e hiahiatia ana te whai wāhi mai o te NAD+.
Mā te NAD+ e pupuri te whakawhitiwhiti matū i waenga i te karihi me ngā mitochondria, ā, ko te ngoikore o te whakawhitiwhiti he tino take o te koroheketanga o ngā pūtau.
Ka taea e te NAD+ te tango i te maha o ngā waehere DNA hē e piki haere ana i te wā e pākia ana e te pūtau, te pupuri i te whakaaturanga noa o ngā ira, te pupuri i te mahi noa o ngā pūtau, me te whakaroa i te koroheketanga o ngā pūtau tangata.
Whakatikahia te kino o te DNA
He matū nui te NAD+ mō te whākōkī whakatika DNA PARP, he pānga nui tōna ki te whakatika DNA, te whakaaturanga ira, te whanaketanga pūtau, te oranga pūtau, te hanga anō i ngā ira, me te pumau o te ira.
Whakahohehia te pūmua roa
E kiia ana ngā sirtuin ko te whānau pūmua roa te ora, ā, he mahi nui tā rātou ki te whakahaere i ngā mahi pūtau, pērā i te mumura, te tipu pūtau, te manawataki circadian, te pākia o te pūngao, te mahi neuronal, me te ātete ki te ahotea, ā, he whākōkī nui te NAD+ mō te hanga pūmua roa te ora. Ka whakahohe i ngā pūmua roa e 7 katoa i roto i te tinana tangata, ka whai wāhi nui ki te ātete ki te ahotea pūtau, te pākia o te pūngao, te aukati i te whakarerekētanga pūtau, te apoptosis me te koroheketanga.
Whakaratohia te pūngao
Ka whakateretere i te whakaputanga o te neke atu i te 95% o te pūngao e hiahiatia ana mō ngā mahi ora. Ko ngā mitochondria i roto i ngā pūtau tangata ngā tipu hiko o ngā pūtau. Ko te NAD+ he coenzyme nui i roto i ngā mitochondria hei whakaputa i te ngota pūngao ATP, hei huri i ngā matūkai hei pūngao e hiahiatia ana e te tinana tangata.
Whakatairanga i te whakahoutanga o ngā oko toto me te pupuri i te ngāwari o ngā oko toto
He kiko tino nui ngā uaua toto mō ngā mahi o te ao. I a tātou e pakeke haere ana, ka ngaro haere te ngāwari o ngā uaua toto, ka pakeke haere, ka matotoru haere, ka whaiti haere, ka puta te "arteriosclerosis." Ka taea e te NAD+ te whakanui ake i te mahi a te elastin i roto i ngā uaua toto, ā, ka mau tonu te ngāwari o ngā uaua toto, ka mau tonu hoki te hauora o ngā uaua toto.
Whakatairanga i te pākia o te tinana
Ko te pākia o te tinana te huinga o ngā tauhohenga matū maha i roto i te tinana. Ka haere tonu te tinana ki te whakawhitiwhiti i ngā mea me te pūngao. Ina mutu tēnei whakawhitiwhitinga, ka mutu anō hoki te ora o te tinana.
I kitea e Ahorangi Anthony me tana tīma rangahau i Te Whare Wānanga o California, USA, ka taea e te NAD+ te whakapai ake i te puhoi o te pākia o ngā pūtau e pā ana ki te koroheketanga, ā, ka whakapai ake i te hauora o te tangata me te whakaroa i te roanga o te ora.
Tiakina te hauora o te ngākau
Ko te ngākau te okana tino nui o te tangata, ā, he mea nui te taumata o te NAD+ i roto i te tinana ki te pupuri i te mahi noa o te ngākau. Tērā pea he hononga te whakahekenga o te NAD+ ki te pathogenesis o ngā mate pūnaha toto maha, ā, he maha ngā rangahau taketake kua whakaū i te pānga o te tāpiringa NAD+ ki ngā mate ngākau.
Ārai i ngā mate o te pūnaha cardiovascular me te roro
Kua whakaatuhia e ngā rangahau e pā ana te nuinga o ngā momo sirtuin e whitu (SIRT1-SIRT7) ki te putanga mai o te mate manawa. E kiia ana ko ngā sirtuin he whāinga agonistic mō te rongoā i ngā mate manawa, inā koa ko te SIRT1.
Ko NAD+ anake te matū mō ngā Sirtuin. Mā te tāpiri i te NAD+ ki te tinana tangata i te wā tika ka taea te whakahohe i te mahi a ia momo Sirtuin, ā, mā reira ka tiakina te hauora o te ngākau me te ārai i ngā mate ngākau.
Whakatairanga i te tipu o te makawe
Ko te tino take o te ngaronga o te makawe ko te ngaronga o te kaha o ngā pūtau whaea o te makawe, ā, ko te ngaronga o te kaha o ngā pūtau whaea o te makawe nā te mea ka heke te taumata NAD+ i roto i te tinana tangata. Kāore i te nui te ATP o ngā pūtau whaea o te makawe hei whakahaere i te hanga pūmua makawe, ā, ka ngaro tō rātou kaha, ka arahi ki te ngaronga o te makawe. Nō reira, mā te tāpiri i te NAD+ ka taea te whakapakari i te huringa waikawa me te whakaputa ATP, kia nui ai te kaha o ngā pūtau whaea o te makawe ki te whakaputa pūmua makawe, ā, ka pai ake te ngaronga o te makawe.
Te rongoā ngota pūtau NAD+
I te pikinga ake o te pakeketanga, ka heke te taumata o te NAD+ (Coenzyme I) i roto i te tinana, ka arahi tika atu ki te mahi a te tinana me te koroheketanga o ngā pūtau! I muri i te pakeketanga waenga, ka heke te taumata o te NAD+ i roto i te tinana tangata i ia tau. I te 50 tau, ko te taumata NAD+ i roto i te tinana he haurua noa iho i tera i te 20 tau. I te 80 tau, ko te taumata NAD+ he tata ki te 1% noa iho o te taumata i te 20 tau.
Nā, he aha te rerekētanga o te paura NAD+ i ētahi atu tāpiringa kei te mākete? Me titiro tata atu tātou ki ētahi o ngā mea matua hei whakaaroaro:
1. Te wātea o te koiora:
Ko tētahi o ngā rerekētanga matua i waenga i te paura NAD+ me ētahi atu tāpiringa ko tōna waatea ki te koiora. He ngāwari te mimiti o te paura NAD+ e te tinana, ā, he pai te whakamahi i ngā coenzymes. I tetahi atu taha, ko ētahi atu tāpiringa he iti ake te waatea ki te koiora, arā, kāore pea te tinana e kaha ki te mimiti me te whakamahi pai i ngā kai hohe.
2. Tikanga mahi:
Ka mahi te paura NAD+ mā te whakakī anō i ngā taumata NAD+ i roto i te tinana, ā, mā reira ka tautoko i ngā mahi pūtau maha. Tērā pea he rerekē ngā tikanga mahi a ētahi atu tāpiringa, e aro ana ki ngā ara, ki ngā pūnaha rānei motuhake i roto i te tinana. Mā te mārama ki ngā tikanga mahi motuhake o ngā tāpiringa rerekē ka āwhina i a koe ki te whakatau ko ēhea te mea pai rawa atu mō ō hiahia takitahi.
3. Rangahau me ngā taunakitanga:
Ina whakaarohia ana tētahi tāpiringa, he mea nui kia arotakehia ngā rangahau me ngā taunakitanga o nāianei e tautoko ana i tōna whai huatanga me tōna haumaru. He maha ngā rangahau kua pā ki te paura NAD+, e whakaatu ana i ōna painga pea mō te hauora pūtau me te roa o te ora. I tētahi atu taha, tera pea he iti noa ngā rangahau a ētahi atu tāpiringa hei tautoko i ā rātou kereme. Mā te mārama ki ngā taunakitanga pūtaiao kei muri i tētahi tāpiringa ka āwhina i a koe ki te whakatau whai whakaaro mō tōna whakamahinga.
4. Ngā hiahia me ngā whāinga whaiaro:
Hei whakamutunga, ko te whakatau ki te whakamahi i te paura NAD+, i ētahi atu tāpiringa rānei, me ahu mai i ō hiahia whaiaro me ō whāinga hauora. Whakaarohia te kōrero ki tētahi tohunga hauora, ki tētahi tohunga kai rānei, hei whakatau ko ēhea tāpiringa te mea tino whai hua ki a koe. Ka taea e ngā āhuatanga pēnei i te tau, te momo noho, me ngā āhuatanga hauora o nāianei te whai wāhi ki te whakatau i te tikanga tāpiringa tino tika.
E 100 tau ngā kaipūtaiao e ako ana i tēnei mea. Ehara a NAD+ i te mea hou, engari he matū kua neke atu i te 100 tau e akohia ana.
I kitea tuatahitia a NAD+ i te tau 1904 e te tohunga matū koiora o Peretānia a Sir Arthur Harden, ā, i muri mai ka toa ia i te Tohu Nobel mō te Matū i te tau 1929.
I te tau 1920, i wehea, i purea hoki e Hans von Euler-Chelpin te NAD+ mō te wā tuatahi, ā, i kitea tōna hanganga dinucleotide, ā, i te tau 1929 ka toa ia i te Tohu Nobel mō te Matū.
I te tau 1930, i kitea tuatahitia e Otto Warburg te tūranga matua o te NAD+ hei coenzyme i roto i te pākia o ngā rauemi me te pūngao, ā, i muri mai ka toa ia i te Tohu Nobel mō te Rongoā i te tau 1931.
I te tau 1980, ko George Birkmayer, he ahorangi i te Tari Matū Hauora i te Whare Wānanga o Graz i Austria, te tuatahi i whakamahi i te NAD+ kua whakaitihia ki te rongoā mate.
I te tau 2012, i kitea e te rōpū rangahau a Leonard Guarente, te rōpū rangahau a te tohunga matū rongonui o te ao a Stephen L. Helfand, me te rōpū rangahau a Haim Y. Cohen, ka taea e NAD+ te whakaroa i ngā tokotoko o Caenorhabditis elegans. Tata ki te 50% te roa o te oranga o ngā nematode, ka taea e ia te whakaroa i te roa o te oranga o ngā namu hua mā te 10%-20% pea, ā, ka taea e ia te whakaroa i te roa o te oranga o ngā kiore tāne mā te neke atu i te 10%.
Kua whakahoutia tonutia, kua whakahoutia hoki ngā tūhuratanga me ngā rangahau a ngā kaipūtaiao mō te ora. I te Hakihea 2013, i whakaputa a David Sinclair, he ahorangi ira i Te Whare Wānanga o Harvard, i te pukapuka "Supplementing NAD with NAD" i roto i te puka mātauranga rongonui o te ao "Cell". "Whai muri i te wiki kotahi o te whakanui ake i te NAD me tētahi kaihoko, kua roa ake te roa o te oranga o ngā kiore mā te 30%. I whakaatuhia e ngā hua rangahau mō te wā tuatahi ka taea e ngā tāpiringa NAD+ te whakakore i te koroheketanga me te whakaroa i te roanga o te oranga. I ohorere te ao i tēnei rangahau, ā, i whakatuwhera i te huarahi ki te rongonui mō ngā tāpiringa NAD hei matū ārai-pakeketanga.
Nā tēnei kitenga whakamiharo, kua whakatūria e te NAD+ tētahi hononga e kore e taea te wehe atu me te ārai i te koroheketanga. I ngā tau tata nei, kua tata te rangahau mō te NAD+ te whakahaere i ngā hautaka mātauranga SCI rongonui pērā i te Science, Nature, me te Cell, ā, koinei te kitenga tino whakamiharo i roto i te hapori hauora. E kiia ana ko tēnei he taahiraa hītori kua mahia e te tangata i roto i te haerenga ki te whawhai ki te koroheketanga me te whakaroa i te roanga o te oranga.
1. Rangahauhia te ingoa rongonui me te māramatanga o te waitohu
Ina whakaarohia he waitohu paura NAD+ motuhake, he mea tika kia rangahauhia te ingoa me te māramatanga o te kamupene. Rapua ngā waitohu e whakatairanga ana i te māramatanga i roto i ā rātou tukanga rapu me te hanga. Ka whakaratohia e ngā waitohu rongonui ngā kōrero taipitopito mō tā rātou kohikohinga paura NAD+, tae atu ki te kounga o ngā rauemi mata me ngā paerewa hanga e piri ana rātou. Hei tāpiri, rapua ngā arotake me ngā whakaaturanga a ngā kiritaki hei aromatawai i te makona me te wheako whānui o ētahi atu kaiwhakamahi ki ngā hua o te waitohu.
2. Aromatawaihia te parakore o te paura NAD+
He mea nui te parakore i te wā e whiriwhiri ana i tētahi waitohu paura NAD+. Me kore he poke me he whakakī i roto i te paura NAD+ kounga teitei, kia mōhio ai koe he hua parakore, he hua whai hua hoki. Rapua ngā waitohu e whakahaere ana i ngā whakamātautau a te hunga tuatoru hei manatoko i te parakore o tā rātou paura NAD+. Mā te whakamātautau a te hunga tuatoru ka whakaratohia he whakapumautanga anō kei te tutuki ngā hua i ngā paerewa parakore teitei rawa atu, ā, kāore he matū kino kei roto.
3. Whakaarohia ngā tukanga hanga me ngā paerewa kounga
He mea nui te mahi a te tukanga hanga ki te kounga o te paura NAD+. Kōwhiria ngā waitohu e whai ana i ngā tikanga whakahaere kounga tino pakari, ā, e piri ana ki ngā Tikanga Hanga Pai (GMP). Mā te tiwhikete GMP ka hangaia ngā hua i roto i te taiao ma, ā, ka whakahaeretia, ka whakaitihia te tūponotanga o te poke, ā, ka whakarite kia pumau te kounga. Hei tāpiri, pātai atu mō te whakapau kaha o te waitohu ki te oranga tonutanga me ngā tikanga matatika mō te hoko rauemi, nā te mea ka taea hoki e ēnei āhuatanga te whakaata i te kounga whānui o te hua.
4. Aromatawai i te waatea o te koiora me te mimiti o te paura NAD+
Ko te wāteatanga koiora e pā ana ki te kaha o te tinana ki te mimiti me te whakamahi i ngā kai hohe i roto i tētahi tāpiringa. I te wā e whiriwhiri ana i tētahi waitohu paura NAD+, whakaarohia te wāteatanga koiora o te hua. Rapua ngā waitohu e whakamahi ana i ngā pūnaha tuku matatau, i ngā hangarau rānei hei whakanui ake i te wāteatanga koiora o te NAD+. Ka uru atu pea tēnei ki ngā āhuatanga pēnei i te micronization, te encapsulation rānei, ka taea te whakapai ake i te mimiti o te NAD+ ki roto i te tinana, ā, ka whakanui ake i tōna whai huatanga.
5. Rapua te rangahau pūtaiao me te rangahau haumanu
Ko ngā waitohu paura NAD+ rongonui e whakarato ana i ngā rangahau pūtaiao me ngā rangahau haumanu hei tautoko i te whai huatanga me te haumaru o ā rātou hua. Rapua ngā waitohu e haumi ana ki te rangahau me te whanaketanga, nā te mea e whakaatu ana tēnei i te whakapau kaha ki te whakaputa hua kounga teitei me ngā hua e ahu mai ana i ngā taunakitanga. Mā te whakamana pūtaiao ka whakarite kua oti te whakamātautau me te aromatawai pakari te paura NAD+, e whakaū ana i tōna kounga me tōna parakore.
Kua uru atu a Suzhou Myland Pharm & Nutrition Inc. ki te pakihi tāpiringa kai mai i te tau 1992. Koinei te kamupene tuatahi i Haina ki te whakawhanake me te hokohoko i te tangohanga kākano karepe.
Me te 30 tau o te wheako, ā, e ārahihia ana e te hangarau matatau me te rautaki R&D tino arotau, kua whakawhanakehia e te kamupene he whānuitanga o ngā hua whakataetae, ā, kua riro hei kamupene auaha mō ngā tāpiringa pūtaiao koiora, te hanga ritenga me ngā ratonga hanga.
Hei tāpiritanga, ko Suzhou Myland Pharm & Nutrition Inc. tētahi kaihanga kua rēhitatia ki te FDA. He hou, he maha ngā mahi a ngā rauemi R&D a te kamupene, ngā whare whakaputa, me ngā taputapu tātari, ā, ka taea te whakaputa matū mai i te mirikaramu ki te tana i te tauine, me te tutuki i ngā paerewa ISO 9001 me ngā whakaritenga whakaputa GMP.
Q: He aha ngā mahi a ngā tāpiringa NAD+?
Ko te tāpiringa A:NAD+ he tāpiringa kai e tāpiri ana ki te coenzyme NAD+ (nicotinamide adenine dinucleotide). He mea nui te mahi a te NAD+ ki te pākia o te pūngao me te whakatikatika pūtau i roto i ngā pūtau.
Q: He tino mahi ngā tāpiringa NAD+?
A: E ai ki ētahi rangahau, ka āwhina pea ngā tāpiringa NAD+ ki te whakapai ake i te pākia o te pūngao pūtau me te whakaroa i te tukanga koroheketanga.
Q: He aha ngā pūtake kai o te NAD+?
A: Ko ngā puna kai o te NAD+ ko te mīti, te ika, ngā hua miraka, ngā pīni, ngā nati me ngā huawhenua. He nui ake te niacinamide me te niacin kei roto i ēnei kai, ka taea te huri hei NAD+ i roto i te tinana.
Q: Me pēhea taku whiriwhiri i tētahi tāpiringa NAD+?
A: I te wā e whiriwhiri ana i ngā tāpiringa NAD+, me rapu tohutohu tuatahi koe i tētahi tākuta, i tētahi tohunga kai rānei, kia mārama ai koe ki ō hiahia kai me tō āhua hauora. Hei tāpiri, whiriwhiria he waitohu rongonui, tirohia ngā kai o te hua me te inenga, ā, whai i ngā aratohu inenga kei te tāpiringa hua.
Whakakape: He kōrero whānui noa iho tēnei tuhinga, kaua e whakamāramatia he tohutohu hauora. Ko ētahi o ngā kōrero o te pou rangitaki i ahu mai i te Ipurangi, ehara i te mea ngaio. Ko tā tēnei paetukutuku anake he whakarōpū, he whakatakotoranga me te whakatika i ngā tuhinga. Ko te kaupapa o te kawe atu i ētahi atu kōrero, ehara i te mea e whakaae ana koe ki ōna tirohanga, e whakaū ana rānei i te pono o ōna ihirangi. Me kōrero tonu ki tētahi tohunga hauora i mua i te whakamahi i tētahi tāpiringa, i te hanga rānei i ngā huringa ki tō tikanga tiaki hauora.
Wā tuku: Akuhata-05-2024
