Kua kitea e ngā kaipūtaiao, i a tātou e pakeke haere ana, ka heke haere te kaha o ā tātou mitochondria, ā, ka iti ake te kaha e puta mai ana. Ka taea e tēnei te arahi ki ngā mate e pā ana ki te koroheketanga pērā i ngā mate neurodegenerative, te mate ngakau, me ētahi atu.
Urolithin A
He matū matū tūturu te Urolithin A, he pānga ārai-waikura me te ārai-whakatipu. Kua kitea e ngā tohunga kai o Te Whare Wānanga o Nova Southeastern i te Hononga o Amerika, mā te whakamahi i te urolithin A hei kai ka taea te whakaroa i te tukanga koroheketanga me te ārai i te whanaketanga o ngā mate e pā ana ki te koroheketanga.
Ka hangaia te Urolithin A (UA) e ō tātou huakita puku i muri i te kai i ngā polyphenols e kitea ana i roto i ngā kai pēnei i te pamekaranete, te rōpere, me te nati. Mā te tāpiringa UA ki ngā kiore pakeke ka whakahohe i ngā sirtuins, ka whakanui ake i te NAD+ me ngā taumata pūngao pūtau. He mea nui, kua whakaaturia te UA ki te whakakore i ngā mitochondria kua pakaru mai i ngā uaua tangata, ā, ka whakapai ake i te kaha, te ātete ki te ngenge, me te mahi hākinakina. Nō reira, ka taea e te tāpiringa UA te whakaroa i te roanga o te ora mā te ārai i te koroheketanga o ngā uaua.
Kāore te Urolithin A e puta tika mai i te kai, engari ko ngā matū pēnei i te waikawa ellagic me ngā ellagitannin kei roto i ngā nati, pamekaranete, karepe me ētahi atu hua ka whakaputa i te urolithin A i muri i te whakapūngao e ngā moroiti puku.
Spermidine
Ko te Spermidine he momo tūturu o te polyamine kua arohia i ngā tau tata nei mō tōna kaha ki te whakaroa i te roanga o te ora me te whakanui ake i te roanga o te hauora. Pērā i te NAD+ me te CoQ10, ko te spermidine he ngota tūturu e heke ana i te pakeketanga. Pērā i te UA, ka hangaia te spermidine e ō tātou huakita puku, ā, ka whakaoho i te mitophagy – te tango i ngā mitochondria kino, kua pakaru. E whakaatu ana ngā rangahau kiore ka taea e te tāpiringa spermidine te tiaki i te mate ngakau me te koroheketanga uri wahine. Hei tāpiri, ko te spermidine kai (e kitea ana i roto i ngā momo kai tae atu ki te soy me ngā witi) i whakapai ake i te mahara i roto i ngā kiore. Me nui ake ngā rangahau hei whakatau mena ka taea te tārua i ēnei kitenga i roto i te tangata.
E ai ki ngā rangahau i whakaputaina i roto i ngā Pūrongo Pūtaiao e ngā kairangahau i te Whare Wānanga Hauora o Kyoto i Hapani, ka whakaitihia e te tukanga koroheketanga noa te kukū o ngā momo tūturu o te spermidine i roto i te tinana. Heoi, kāore anō kia kitea tēnei āhuatanga i roto i ngā rautau kua hipa;
Ka taea e te Spermidine te whakatairanga i te autophagy.
Ko ngā kai he nui te spermidine ko: ngā kai witi katoa, te rimu, ngā harore shiitake, ngā nati, te rarauhe, te purslane, me ētahi atu.
kurukimini
Ko te curcumin te matū hohe i roto i te turmeric he āhuatanga anti-inflammatory me te antioxidant.
Kua kitea e ngā tohunga koiora whakamātautau o te Polish Academy of Sciences ka taea e te curcumin te whakaiti i ngā tohu o te koroheketanga me te whakaroa i te haere whakamua o ngā mate e pā ana ki te koroheketanga e whai pānga tika ana ki ngā pūtau kua koroheke, ā, mā reira ka roa ake te roa o te oranga.
Haunga te turmeric, ko ngā kai he nui te curcumin ko: te kanekane, te kāriki, te riki, te pepa pango, te māti me te kari.
Ngā tāpiringa NAD+
I ngā wāhi kei reira ngā mitochondria, kei reira te NAD+ (nicotinamide adenine dinucleotide), he ngota e tika ana mō te whakanui ake i te whakaputanga pūngao. Ka heke noa te NAD+ i te pakeketanga, e rite ana ki te hekenga o te mahi mitochondrial e pā ana ki te pakeketanga. Koinei tētahi o ngā take i whakawhanakehia ai ngā kaiwhakatairanga NAD+ pērā i te NR (Nicotinamide Ribose) hei whakaora i ngā taumata NAD+.
E whakaatu ana ngā rangahau mā te whakatairanga i te NAD+, ka taea e te NR te whakarei ake i te whakaputanga pūngao mitochondrial me te ārai i te ahotea e pā ana ki te koroheketanga. Tērā pea ka whakapai ake ngā tāpiringa NAD+ i te mahi uaua, te hauora o te roro, me te pākia o te tinana, me te whawhai pea ki ngā mate neurodegenerative. Hei tāpiri, ka whakaitihia e rātou te pikinga o te taumaha, ka whakapai ake i te aro ki te insulin, ā, ka whakataurite i ngā taumata lipid, pērā i te whakaheke i te cholesterol LDL.
Te wā tuku: Hurae-24-2024
