He aha ngā mea me mōhio koe mō te palmitoylethanolamide (PEA)?

Ko te Palmitoylethanolamide (PEA) he amide waikawa ngako tūturu kua arohia mō ōna painga hauora pea. Kei roto i ngā kiko maha puta noa i te tinana tēnei matū, ā, e kī ana ngā rangahau ka taea e te palmitamideethanol (PEA) te whakaiti i te mumura, te whakaiti i te mamae, ā, ka taea hoki te whakatairanga i te hauora o te puku me te whakaroa i te koroheketanga. Tērā pea he maha ngā painga hauora. Ka tūhuratia e ngā tuhinga e whai ake nei ngā painga hauora o te palmitoylethanolamide (PEA), me pēhea tana mahi ki te tinana tangata, me pēhea te kimi i te palmitoylethanolamide (PEA) kounga teitei.

He aha te palmitoylethanolamide (PEA)?

Palmitoylethanolamide (PEA) he matū rite ki te endocannabinoid e kitea ana mō ōna āhuatanga whakamamae mamae me te ārai-mumura. Haunga te hanga e te tinana, ka kitea te PEA i roto i ngā momo kai tae atu ki: te tiihi, te toene hua manu, te mīti, te miraka, te pīnati, te lecithin soy.

I mōhio koe? Ina tūtaki te tinana ki ngā ahotea, pērā i te whara, te mumura rānei, ka whakarerekē ngā taumata PEA hei pupuri i te homeostasis pūtau.

He pēhea te pānga o te palmitoylethanolamide ki te tinana o te tangata?

Kāore anō kia tino mārama ngā kaipūtaiao ki te tikanga mahi a te palmitoylethanolamide. Ahakoa rā, kua roa te ara kua tae mai, nā te Ahorangi Rita Levi-Montalcini, nāna i whakamārama te tikanga mahi whānui o te palmitoylethanolamide i te tau 1992-1996. Mai i taua wā, kei te haere tonu tana rangahau i ngā pānga o te palmitoylethanolamide ki te mamae neuropathic me ngā mate pāwera.

E whā pea ngā painga nui o te Palmitoylethanolamide ki te hauora o te tangata:

●Whakamamae i te urupare mumura.

●Whakaitihia te whakahohenga o ngā pūtau mast (mate pāwera).

●Whakapakari i te mahi a te pūnaha hemp taketake.

●Whakahohe i ngā kaiwhakawhiwhi motuhake o te tinana.

He pēhea te whakamahinga a te PEA i ōna pānga ārai-mumura me te whakamamae i te mamae?

Ko ngā painga hauora o te PEA ko ngā pānga ki ngā pūtau ārai mate e whakahaere ana i te mumura, inā koa i roto i te roro. Tērā pea ka āwhina te PEA ki te whakaiti i te whakaputanga o ngā matū mumura. Heoi, ko te mahi nui a te PEA ki ngā kaiwhakawhiwhi i runga i ngā pūtau, e whakahaere ana i ngā āhuatanga maha o te mahi a te pūtau. Ka kiia ēnei kaiwhakawhiwhi ko ngā PPAR. Ka taea e te PEA me ētahi atu matū e āwhina ana ki te whakahohe i te PPAR te whakaiti i te mamae, ā, ka taea hoki te whakanui ake i te pākia o te tinana mā te tahu ngako, te whakaiti i ngā triglycerides toto, te whakanui ake i te cholesterol HDL toto, te whakapai ake i te whakahaere huka toto, me te āwhina i te whakaheke taumaha.

Ngā Painga o te Palmitoylethanolamide

Nā te mea he pānga mamae me te ārai-mumura tōna, e kī ana ngā rangahau ka āwhina pea te PEA i ngā momo mate mamae, pērā i te fibromyalgia, te sciatica, me te osteoarthritis.

1. Whakamamae i te mamae me te urupare mumura

He raruraru nui te mamae mau tonu e pāngia ana e ngā tūroro huri noa i te ao, ā, i te pakeketanga o te taupori, ka nui haere te kino o tēnei raruraru. Ko tētahi o ngā mahi a te palmitoylethanolamide he āwhina pea ki te whakamamae i te mamae me te mumura. Ka taunekeneke te palmitoylethanolamide me ngā kaiwhakawhiwhi CB1 me CB2, he wāhanga nui ēnei o te pūnaha hemp taketake. Ko tēnei pūnaha te kawenga mō te pupuri i te homeostasis, te taurite rānei i roto i te tinana.

Ina puta he whara, he mumura rānei, ka tukuna e te tinana ngā matū hemp taketake hei āwhina i te whakahaere i te urupare ārai mate. Tērā pea ka āwhina te palmitoylethanolamide ki te whakanui ake i ngā taumata hemp taketake i roto i te tinana, ā, mā reira ka whakamamae i te mamae me te mumura.

Hei tāpiritanga, ka taea e te palmitoylethanolamide te whakaiti i te tukunga o ngā matū mumura me te whakaiti i ngā urupare mumura whānui o te pūnaha io. Nā ēnei pānga ka waiho te palmitoylethanolamide hei taputapu pea hei āwhina i te whakahaere i te mamae me ngā urupare mumura. E whakaatu ana ngā rangahau he whai hua pea te palmitoylethanolamide mō te mamae sciatica me te carpal tunnel syndrome.

2. Te mate pukupuku o te uaua

He maha ngā rangahau e kī ana ka āwhina pea te PEA ki te whakaiti i ngā tohu o te fibromyalgia, he mate pūnaha io mau tonu e puta ai te mamae whānui. Ina whakamahia hei tāpiritanga ki ngā rongoā tuku iho, ka whakaitihia e te kai PEA te kaha o te mamae, ā, ka whakapai ake i te kounga o te oranga i roto i te wā. E ai ki tētahi rangahau, ko te tango i te PEA mō ngā marama e toru ka tino whakaiti i te mamae o te hunga whai fibromyalgia.

3. Mamae tuara

E tohu ana ngā rangahau tuatahi i te whai huatanga pea o te PEA mō te mamae o te tuara. I whakaatuhia e tētahi rangahau tirotiro i te tau 2017 i whakaitihia e te PEA te kaha o te mamae i roto i ngā tūroro i pāngia e te mate pokanga tuara i rahua.

Ko te hunga e pāngia ana e te sciatica, he mamae e toro atu ana i te tuara o raro ki raro i tētahi, i ngā waewae e rua rānei, ka kitea pea he whakamarie i muri i te tango i te PEA. I rangahauhia e tētahi whakamātautau matapōkere, matapo-rua, placebo-controlled ngā pānga o te PEA horopeta nui me te iti ki te placebo. I heke te mamae mā te neke atu i te 50% i roto i te rōpū horopeta nui. Ahakoa kāore i eke te PEA horopeta iti ki te taumata whakamarie mamae rite ki te horopeta nui, he nui ake te whai huatanga o ngā horopeta e rua i te placebo.

4. Te mate wheua me te wheua

Tērā pea he pai te PEA mō te hunga e pāngia ana e te osteoarthritis, he mate e tohuhia ana e te pirau o te kiriuhi hononga me te wheua. I kitea e ngā kaiuru i tētahi rangahau i whiwhi PEA he whakapainga nui i roto i ngā kaute Western Ontario me McMaster Universities Osteoarthritis Index (WOMAC) ki te whakaritea ki te rōpū placebo. Ko te WOMAC he pātai i hangaia hei aromatawai i te āhua me ngā tohu (hei tauira, te mamae, te pakari, te mahi tinana) i roto i ngā tūroro e pāngia ana e te osteoarthritis turi me te hope.

I roto i tētahi atu rangahau i uru atu ai ngā tūroro e pāngia ana e te mamae o te temporomandibular arthritic (TMJ) e pā ana ki te osteoarthritis, i whakaatuhia ko te tāpiringa PEA i whakapai ake i te kaha o te mamae i muri i ngā rā 14 ki te whakataurite ki te ibuprofen. Ko te rōpū i hoatuhia he PEA mō ngā rā 14 i whakaatu i te whakapainga nui ake i te whakatuwheratanga o te waha (he ine i te whakamamae mamae) i te rōpū ibuprofen.

5. Mamae neuropathic

E whakaatu ana ngā rangahau take tuatahi me ngā whakamātautau kararehe ka āwhina pea te PEA i te mamae neuropathic (nā te kino o ngā io e kawe ana i ngā karere i waenga i te roro me te taurakira), inā koa i roto i te hunga e pāngia ana e te mate carpal tunnel, te neuropathy mate huka, te chemotherapy. Ko te hunga e pāngia ana e te neuropathy peripheral, te mamae pelvic mau tonu, me te mamae e pā ana ki te whiu me te multiple sclerosis. Me whai atu ngā whakamātautau haumanu hei whakatau i te whai huatanga o te PEA ki te whakatau i te mamae neuropathic.

6. Te koroheketanga hauora

Ko te whakaroa i te tukanga koroheketanga he whāinga whai hua e whaia ana e te tini o ngā kaipūtaiao huri noa i te ao. E kiia ana ko te Palmitoylethanolamide he tāpiringa ārai-pakeketanga e āwhina ana ki te tiaki i ngā pūtau mai i te kino waikura, koinei te tino take o te koroheketanga.

Ina pāngia ngā pūtau e te nui rawa o ngā rauropi kore utu, ka puta pea ngā tauhohenga waikura, ka arahi ki te matenga o ngā pūtau i te wā o mua. Ko te kai i ngā kai kino, te momi hikareti, me ētahi atu pānga taiao pēnei i te parahanga o te hau ka whakanui ake i te kino waikura. Ka ārai pea te Palmitoylethanolamide i tēnei kino mā te tango i ngā rauropi kore utu me te whakaiti i te urupare mumura whānui i roto i te tinana.

Hei tāpiritanga, kua whakaaturia te kaha o te palmitoylethanolamide ethanol ki te whakaoho i te hanga o te collagen me ētahi atu pūmua kiri nui. Nō reira, ka whakaitihia pea te āhua o ngā kita me ngā raina angiangi, ka mahi hei tiaki i roto i ngā pūtau.

He kaihanga kua rēhitatia ki te FDA a Suzhou Myland Pharm & Nutrition Inc. e whakarato ana i te paura Palmitoylethanolamide (PEA) kounga teitei, parakore hoki.

I Suzhou Myland Pharm, e whakapau kaha ana mātou ki te whakarato i ngā hua kounga teitei rawa atu i ngā utu pai rawa atu. Kua whakamatautauria te parakore me te kaha o tā mātou paura Palmitoylethanolamide (PEA), kia whiwhi ai koe i tētahi tāpiringa kounga teitei ka taea e koe te whakawhirinaki. Ahakoa e hiahia ana koe ki te tautoko i te hauora pūtau, ki te whakapakari i tō pūnaha ārai mate, ki te whakarei ake rānei i te hauora whānui, ko tā mātou paura Palmitoylethanolamide (PEA) te whiringa tino pai.

Me te 30 tau o te wheako, me te mea hoki e ārahihia ana e te hangarau matatau me ngā rautaki R&D kua tino arotauhia, kua whakawhanakehia e Suzhou Myland Pharm he whānuitanga o ngā hua whakataetae, ā, kua riro hei kamupene auaha mō ngā tāpiringa pūtaiao koiora, te hanga ritenga me ngā ratonga hanga.

Hei tāpiritanga, he kaihanga kua rēhitatia ki te FDA a Suzhou Myland Pharm. He hou, he maha ngā mahi a ngā rauemi R&D a te kamupene, ngā whare whakaputa, me ngā taputapu tātari, ā, ka taea te whakaputa matū mai i te mirikaramu ki te tana i te tauine, me te tutuki i ngā paerewa ISO 9001 me ngā whakaritenga whakaputa GMP.