Kaihanga paura RU58841 Nama CAS: 154992-24-2 99.0% te parakore iti rawa mō ngā kai tāpiringa
Ngā Tawhā Hua
| Ingoa hua | 4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile |
| Ingoa kē atu | RU58841 |
| Nama CAS | 154992-24-2 |
| Tātai ngota | C17H18F3N3O3 |
| Taumaha ngota | 369.34 |
| Te parakore | 99.0% |
| Āhua | paura mā |
| Te tākai | 1kg/pēke |
| Tono | Whakatipu makawe |
Whakataki hua
Ko te RU58841 (e mōhiotia ana ko te RU-58841) he matū, ka whakataetae te RU58841 ki te dihydrotestosterone hei pupuri i ngā taumata DHT ki roto i te awhe noa, ā, mā reira ka whakahaere i te huringa tipu o te makawe. Ka whakaoho i te hurihanga o ngā follicle makawe hou ki ngā follicle makawe anagen mā te tomo ki te wāhanga anagen. Mā te tuku i ngā follicle kua pakaru kia hoki ki te wāhanga tipu noa ka āwhina i ngā pūtau ki te ora. Ka whakanui ake hoki i te rere o te toto ki ngā follicle kua pakaru, ā, ka āwhina i a rātou ki te whakaora anō. I tētahi atu taha, ka mahi te RU58841 (RU-58841) mā te herea ki ngā kaiwhakawhiwhi androgen i roto i ngā follicle makawe. Nō reira, kāore he wāhi o ngā androgen ki te herea me te tīmata i te tauhohenga mekameka o te androgenetic alopecia me te tīmata i te tukanga e kiia nei ko te miniaturization. Kua whakaaturia ka whakakorea e ia tēnei karere ngaro makawe kia taea ai te haere tonu o te tipu makawe noa.
Āhuatanga
(1) Ka taea te ārai i te ngaronga o te makawe: He aukati homoni motuhake a RU58841, ka taea te ārai i te whakakotahitanga o ngā pūtau androgen me ngā pūtau huruhuru kiriuhi, ā, ka whakaiti i te tūponotanga o te ngaronga o te makawe.
(2) He pai te mimiti: He iti te taumaha ngota o te RU58841, he māmā te hanganga, ā, he ngāwari ki te mimiti. Ka tere te uru ki te tinana, ā, ka tere te pānga.
(3) Te tino whiriwhiri ki te androgen: Ka taea e te RU58841 te aukati i te mahi a te androgen me te kore e pā ki ētahi atu homoni.
(4) Roa te mahi: He roa te haurua-ora o te RU58841 i roto i te tinana, ka taea te aukati tonu i te pānga o te androgen, ā, ka taea te roa o te wā whai hua ki te 48 hāora.
(5) Te parakore teitei: Mā te tangohanga taiao me te tukanga hanga pai, ka taea e te whanaketanga o te RU58841 te whiwhi hua parakore teitei.
Ngā tono
I roto i ngā rangahau me ngā whakamātautau haumanu, kua whakaatuhia te kaha o te RU58841 ki te whakanui ake i te tere whakaputa uri pūtau i roto i ngā pūtau stromal, ki te whakanui ake i te tipu pūtau i roto i ngā pūtau rau pakiaka o waho, me te whakanui ake i te whānui me te matotoru o te makawe, nō reira he rongoā rangahau te RU58841 mō te rongoā i te androgenetic alopecia. Ko te kaupapa matua o te mahi ko te aukati i te huinga o te DHT me te AR o ngā follicle makawe, e whakamahia ana hei rongoā i te ngaronga makawe me ngā raruraru ngaronga makawe.
