5-Amino-1-methylquinolinium chloride CAS No.:42464-96-0 98.0% te parakore iti rawa | kaihanga kai tāpiringa
Ngā Tawhā Hua
| Ingoa hua | 5-Amino-1-methylquinolinium chloride（5-amino-1MQ） |
| Ingoa kē atu | 5-amino-1MQ5-Amino-1-mq pūhaumāota 5-Amino-1-methylquinolinium chloride 5-Amino-1-methylquinolin-1-ium chloride 5-AMINO-1-METHYLQUINOLIN-1-IUM CHLOEIDE 5-Amino-1-methyl-1-quinolinium chloride |
| Nama CAS | 42464-96-0 |
| Tātai ngota | C₁₀H₁₁ClN₂ |
| Taumaha ngota | 194.6 |
| Te parakore | 98% |
| Āhua | Parauri ki te parauri whero totoka |
| Te tākai | 1kg/pēke, 25kg/peera |
| Tono | Rauemi Mata o te Tāpiringa Kai |
Whakataki hua
Ko te 5-Amino-1-methylquinolinium chloride he whākōkī e nui rawa ana te whakaputa i te wā e koroheke ana ngā uaua angaanga, ā, e pā ana ki te whakatikatika i te kino o te ara NAD+, te koretake o te mahi sirtuin1, me te pikinga o te koroheketanga o ngā pūtau take uaua. Ka whakatairanga te 5-Amino-1-methylquinolinium chloride i te rerekētanga o te myoblast i roto i te vitro, ā, ka whakarei ake i te hanumitanga me te whakaoranga o ngā pūtau take uaua i roto i ngā kiore kua pakeke. Ko te 5-Amino-1-methylquinolinium chloride he aukati kaha hoki o te nicotinamide N-methyltransferase (NNMT), e herea ana ki ngā toenga pae herenga NNMT. Ka whakatairanga te 5-Amino-1-methylquinolinium chloride i te rerekētanga o te myoblast i roto i te vitro, ā, ka whakarei ake i te hanumitanga me te whakaoranga o ngā pūtau take uaua i roto i ngā kiore kua pakeke. I roto i ēnei, kua kitea houtia te whākōkī cytosolic nicotinamide N-methyltransferase (NNMT) hei whakahaere i ngā taumata o ngā matū mua o te nicotinamide e hiahiatia ana mō te biosynthesis NAD+, nō reira he mahi nui tana ki te whakahaere i te ara whakaora NAD+ me te pākia o te pūtau.
Ka mahi te 5-Amino-1-Methylquinolinium Chloride i roto i tō microbiome ki te whakaiti i te kiko ngako (ngako) me te āwhina i a koe ki te whakaiti i tō taumaha. Ina kohia ngā pūtau ngako tāpiri, ka nui rawa te hanga a tō tinana i tētahi whākōkī e mōhiotia ana ko te NNMT (nicotinamide N-methyltransferase). Ka nui ake te NNMT, ka nui ake te whakanui ake o tō tinana i te mumura me te penapena ngako. Ka aukati te 5-Amino-1-Methylquinolinium Chloride i te NNMT, ka taea ai e tō tinana te whakaheke i te taumaha nui.
Āhuatanga
(1) Teitei o te parakore: Ka taea e te 5-Amino-1-methylquinolinium chloride te whiwhi hua parakore teitei mā roto i ngā tukanga whakaputa kua whakatikatikaina. Ko te tikanga o te parakore teitei he pai ake te waatea o te koiora.
(2) Te arotahi: Ka arotahi motuhake te 5-Amino-1-methylquinolinium chloride ki te whākōkī NNMT, ā, ka taea te aukati i tana mahi, ā, ka pā ki te ara pākia o te nicotinamide.
(3) Te Pūmautanga: He pai te pumau o te 5-Amino-1-methylquinolinium chloride, ā, ka taea e ia te pupuri i tōna kaha me tōna pānga i raro i ngā taiao me ngā tikanga rokiroki rerekē.
(4) Ngā tūmanakohanga whanaketanga: Nā ngā āhuatanga rerekē o te 5-Amino-1-methylquinolinium chloride, kua arohia whānuitia tōna whanaketanga, ā, he whānui hoki ngā tūmanakohanga rangahau me te tono.
Ngā tono
Ko te 5-Amino-1-methylquinolinium chloride he aukati nicotinamide N-methyltransferase (NNMT) e whakatairanga ana i te rerekētanga o te myoblast. Ka taea hoki te whakamahi i te 5-Amino-1-methylquinolinium chloride hei tāpiringa hei āwhina i te whakaiti i te taumaha me te ngako me te whakapai ake i te ngako ate.
